DoE and formulation chemistry

Can I use design of experiments to improve my formulation?

Virtual Training DoE Course

With the current restrictions on travel and face to face training, we have moved our training online. In collaboration with Scientific Update we ran our popular DoE course from the 5th-8th October 2020 and the QbD course from the 9th – 13th November 2020.

Reducing experiment numbers

DoE is a very powerful tool to efficiently look at the cause and effect relationship between factors such as temperature and concentration, and responses such as conversion and impurity formation. DoE looks at each factor at 2 or more levels.

Risk assessments in the Quality by Design Process

There is no doubt if you are working in the pharmaceutical industry you should be employing the Quality by Design principles to achieve robust processes and consistently high quality products. Successful risk assessment is a fundamental aspect of QbD, however, risk analysis is a subjective process and is open to human bias and inaccuracy.

How to quickly change from batch to continuous processing

Adopting a new technology may sound daunting but it doesn’t have to be complicated. If you have been thinking about moving to continuous processing for a while but don’t know where to start, employing experimental design is a systematic way to quickly determine the optimum operating conditions for a flow process.

How we are using DoE with clients

DoE can be applied to many different industries and processes

Solvent Selection for a Greener Process

Are you hoping to improve the greenness of your chemical processes? There are several drivers leading companies towards adopting the green chemistry principles, which aim for waste prevention, improved process safety, increased energy efficiency and reduced health impact. New regulations as well as the beneficial reduced cost associated with a greener process, are two key motivators.

DoE Course for Formulators

Following a successful webinar, registration is now open for our upcoming DoE training in association with iFormulate: Design of Experiments for Formulators.

Challenges in Catalysis for Pharmaceuticals and Fine Chemicals VI - poster deadline extension 1st october

Registration is now open for Challenges in Catalysis for Pharmaceuticals & Fine Chemicals VI organised by the RSC Applied Catalysis Group and the SCI Fine Chemicals Group. The event will be held on Wednesday, 14th November 2018 at the RSC Burlington House Piccadilly. This conference will cover topics in the application of catalysis including base metal catalysis, biocatalysis, metathesis, photoredox catalysis and reaction progress kinetics. The challenges conference series brings the usual mix of relevant academic talks and industrial application. We hope you find it interesting and look forward to seeing you there.

Analysis and Experimental Design

Is a poor analytical technique preventing you from moving forward with your chemistry? We often see cases where the analysis of a reaction intermediate is highly problematic and implies inconsistent results, when it is in fact the analytical method which is giving rise to the problems.